SELECT 
  cscart_discussion_posts.*, 
  cscart_discussion_messages.message 
FROM 
  cscart_discussion_posts 
  LEFT JOIN cscart_discussion_messages ON cscart_discussion_messages.post_id = cscart_discussion_posts.post_id 
WHERE 
  cscart_discussion_posts.thread_id IN (3167, 3168, 3169, 3170) 
  AND cscart_discussion_messages.message <> '' 
  AND cscart_discussion_posts.status = 'A' 
ORDER BY 
  cscart_discussion_posts.timestamp DESC 
LIMIT 
  0, 10

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "7.81"
    },
    "ordering_operation": {
      "using_filesort": true,
      "cost_info": {
        "sort_cost": "3.60"
      },
      "nested_loop": [
        {
          "table": {
            "table_name": "cscart_discussion_posts",
            "access_type": "range",
            "possible_keys": [
              "PRIMARY",
              "thread_id",
              "thread_id_2"
            ],
            "key": "thread_id_2",
            "used_key_parts": [
              "thread_id",
              "status"
            ],
            "key_length": "6",
            "rows_examined_per_scan": 4,
            "rows_produced_per_join": 4,
            "filtered": "100.00",
            "index_condition": "((`primapearl_r_new`.`cscart_discussion_posts`.`thread_id` in (3167,3168,3169,3170)) and (`primapearl_r_new`.`cscart_discussion_posts`.`status` = 'A'))",
            "cost_info": {
              "read_cost": "2.41",
              "eval_cost": "0.40",
              "prefix_cost": "2.81",
              "data_read_per_join": "1K"
            },
            "used_columns": [
              "post_id",
              "thread_id",
              "name",
              "timestamp",
              "user_id",
              "ip_address",
              "status"
            ]
          }
        },
        {
          "table": {
            "table_name": "cscart_discussion_messages",
            "access_type": "eq_ref",
            "possible_keys": [
              "PRIMARY"
            ],
            "key": "PRIMARY",
            "used_key_parts": [
              "post_id"
            ],
            "key_length": "3",
            "ref": [
              "primapearl_r_new.cscart_discussion_posts.post_id"
            ],
            "rows_examined_per_scan": 1,
            "rows_produced_per_join": 3,
            "filtered": "90.00",
            "cost_info": {
              "read_cost": "1.00",
              "eval_cost": "0.36",
              "prefix_cost": "4.21",
              "data_read_per_join": "86"
            },
            "used_columns": [
              "message",
              "post_id"
            ],
            "attached_condition": "(`primapearl_r_new`.`cscart_discussion_messages`.`message` <> '')"
          }
        }
      ]
    }
  }
}